We are excited to announce the release of the first version of SeqCVIBE, a platform for the interactive exploration, analysis, visualization and cataloguing of RNA-Seq data which was developed by HybridStat Predictive Analytics with Elixir-GR funding resources.

SeqCVIBE is a Shiny web application for the interactive data exploration, analysis, visualization and genome browsing of large RNA-Seq datasets. SeqCVIBE is powered by a lite version of the metaseqR Bioconductor package for gene expression analysis and by JBrowse for genome browsing. In addition, it deploys the powerful reactive environment of Shiny to offer a real-time interactive interface. SeqCVIBE allows for several on-the-fly sub-dataset creations and visualizations and calculations, such as averaging genomic tracks over specific regions and calculating RNA abundance in custom possibly non-annotated regions (e.g. novel long non-coding RNAs). Other interactive analysis capabilities of SeqCVIBE include on-the-fly differential expression analysis with interactive visualizations and exploration, clustering analysis, correlation analysis and dimensionality reduction. In addition, SeqCVIBE is at the same time a database for pre-analysed data where the user can navigate and explore the results, perform basic analyses in various ways and save analysis sessions.

SeqCVIBE is available at http://elixir-seqcvibe.hybridstat.gr. Source code is available through GitHub.